It goes beyond one community.
PrEP is for women, too.
The Centers for Disease Control and Prevention (CDC) recommends that all sexually active adults and adolescents be informed about PrEP.
All people featured on this page are actor portrayals.
All people featured on this page are actor portrayals.
About19%
of new HIV diagnoses in the United States in 2022 were
among women, but only 9% of PrEP users in 2024 were women.
87%
of new HIV diagnoses in the United
States in 2022 among all transgender people were transgender women.
One office visit, every six months. 2 times a year for HIV prevention.
One office Two injections per visit, after starter dosing.
YEZTUGO was studied in two clinical trials, including one focused exclusively on women.
THE PURPOSE 1 STUDY
Included around 2100 young cisgender women and adolescent girls who received YEZTUGO, including those who became pregnant or started breastfeeding,* in South Africa and Uganda.
*People were allowed to stay in the study and continue on YEZTUGO
if they became pregnant or started lactating.
HIV prevention is a crucial
part of healthcare for women.
When you see your healthcare provider, you ask about screenings, vaccines, and birth control—HIV prevention belongs in the conversation too.
Learn more about YEZTUGO
DESCOVY is the smallest PrEP pill available and is one pill, once a day as part of your daily HIV prevention routine
Learn more about YEZTUGO (lenacapavir)
[YEZTUGO® DTC Broadcast Spot A Transcript]
TEXT ON-SCREEN:
Actor Portrayals.
Twice-yearly PrEP is here
After completing starter dosing: 2 pills by mouth and 2 injections at your healthcare provider’s office, then 2 more pills at home the next day.
PrEP = Pre-exposure prophylaxis.
ANNOUNCER:
Twice-yearly PrEP is here
One office visit every six months…
TEXT ON-SCREEN:
ONE office visit every 6 months
After completing starter dosing: 2 pills by mouth and 2 injections at your healthcare provider’s office, then 2 more pills at home the next day.
ANNOUNCER:
…two times a year for HIV prevention.
TEXT ON-SCREEN:
2x yearly
After completing starter dosing: 2 pills by mouth and 2 injections at your healthcare provider’s office, then 2 more pills at home the next day.
ANNOUNCER:
That’s one 2 PrEP.
TEXT ON-SCREEN:
ONE2PrEP
ANNOUNCER:
That’s YEZTUGO. YEZTUGO is an injectable prescription medicine that helps protect against HIV through sex.
TEXT ON-SCREEN:
[YEZTUGO logo]
YEZTUGO is a prescription medicine that is used for HIV-1 PrEP to reduce the risk of getting HIV-1 in adults and adolescents who weigh at least 77 pounds (at least 35 kg).
ANNOUNCER:
One office visit every six months.
TEXT ON-SCREEN:
[YEZTUGO logo]
One during your Winter Glam
2 injections per office visit every 6 months.
ANNOUNCER:
One during your winter glam.
TEXT ON-SCREEN:
[YEZTUGO logo]
One during your Summer Glow
2 injections per office visit every 6 months.
ANNOUNCER:
And one during your summer glow.
TEXT ON-SCREEN:
[YEZTUGO logo]
One during your Winter Time
2 injections per office visit every 6 months.
ANNOUNCER:
And one during your winter time.
TEXT ON-SCREEN:
[YEZTUGO logo]
One during your Summer Shine
2 injections per office visit every 6 months.
ANNOUNCER:
And one during your summer shine.
TEXT ON-SCREEN:
[YEZTUGO logo]
You must be HIV negative to receive YEZTUGO and get tested for HIV before each injection.
ANNOUNCER:
You must be HIV negative to receive YEZTUGO and get tested for HIV before each injection.
TEXT ON-SCREEN:
[YEZTUGO logo]
If you think you were exposed to HIV or have flu-like symptoms, tell your healthcare provider right away. HIV testing may be needed.
ANNOUNCER:
If you think you were exposed to HIV or have flu-like symptoms, tell your healthcare provider right away. HIV testing may be needed.
TEXT ON-SCREEN:
[YEZTUGO logo]
YEZTUGO does not prevent other sexually transmitted infections.
ANNOUNCER:
YEZTUGO does not prevent other sexually transmitted infections.
TEXT ON-SCREEN:
[YEZTUGO logo]
Practice safer sex and get YEZTUGO as scheduled. Missing doses increases your chance of getting HIV.
ANNOUNCER:
Practice safer sex and get YEZTUGO as scheduled. Missing doses increases your chance of getting HIV.
TEXT ON-SCREEN:
[YEZTUGO logo]
Tell your provider about your medical conditions, if you are pregnant or plan to be, and all the medicines and supplements you take, as YEZTUGO may affect some medicines.
ANNOUNCER:
Tell your provider about your medical conditions, if you are pregnant or plan to be, and all the medicines and supplements you take, as YEZTUGO may affect some medicines.
TEXT ON-SCREEN:
[YEZTUGO logo]
The most common side effects are injection site reactions, headache, and nausea. Rare serious injection site reactions can occur, so tell your provider about any side effects.
ANNOUNCER:
The most common side effects are injection site reactions, headache, and nausea. Rare serious injection site reactions can occur, so tell your provider about any side effects.
TEXT ON-SCREEN:
[YEZTUGO logo]
≥99.9% stayed HIV negative
Compared to ≥98.5% with a once-daily PrEP pill (FTC/TDF) in each of two 1-year studies.
ANNOUNCER:
Ninety-nine point nine percent of people stayed HIV negative.
TEXT ON-SCREEN:
[YEZTUGO logo]
Two injections per office visit every six months.
Learn more at Yeztugo.com
You could pay as little as $0 per month.
Restrictions apply. See Terms and Conditions.
Gileadpriceinfo.com
1-844-YEZTUGO
[GILEAD logo]
ANNOUNCER:
Ask a healthcare provider if YEZTUGO is right for you.
There's more to discover:
Take the first step in starting the conversation about YEZTUGO.
Find out what starting YEZTUGO could look like for you.
See how YEZTUGO could cost as little as $0. Restrictions apply.
YEZTUGO is a prescription medicine used as HIV-1 PrEP (pre-exposure prophylaxis) to reduce the risk of getting HIV-1 in adults and adolescents who weigh at least 77 pounds. You must be HIV negative before and while receiving YEZTUGO.
YEZTUGO is a prescription medicine used as HIV-1 PrEP (pre-exposure prophylaxis) to reduce the risk of getting HIV-1 in adults and adolescents who weigh at least 77 pounds. You must be HIV negative before and while receiving YEZTUGO.
Important Safety Information
What is the most important information I should know about YEZTUGO?
Before and while receiving YEZTUGO:
Tap for Important Safety Information, including an important warning on the risk of drug resistance if you become HIV positive and only take YEZTUGO.
- You must be HIV negative before you start and while receiving YEZTUGO. Get an HIV test before starting, before each injection, and when your healthcare provider tells you. If you think you were exposed to HIV while receiving YEZTUGO, talk to your healthcare provider as you may need an HIV test.
- Some HIV tests may not detect HIV in a person who recently acquired HIV. Tell your healthcare provider if you had a flu-like illness within the last month before starting or while receiving YEZTUGO. Symptoms of new HIV infection include tiredness, fever, joint or muscle aches, headache, sore throat, vomiting or diarrhea, rash, night sweats, and/or enlarged lymph nodes in the neck or groin.
- YEZTUGO does not prevent other sexually transmitted infections (STIs). Get tested for other STIs and practice safer sex by using condoms to reduce the risk of getting STIs.
- YEZTUGO is not approved to treat HIV. You must immediately take other medicines if you get HIV. If you have HIV and only receive YEZTUGO, your HIV may become harder to treat.
- Follow the YEZTUGO dosing schedule, which includes returning to a healthcare provider for your scheduled injections every 6 months. Missing scheduled injections or tablets can increase your chances of getting HIV.
- To further help reduce your risk of getting HIV:
- Know your HIV status and the HIV status of your partner(s). If they are living with HIV, your risk of getting HIV is lower if they are taking effective HIV treatment.
- Talk to your healthcare provider about all the ways to help reduce the risk of getting HIV.
Who should not receive or take YEZTUGO?
- Do not receive YEZTUGO if you already have HIV or do not know your HIV status. If you have HIV, you will need to take other medicines to treat it. YEZTUGO is not approved to treat HIV and is only for reducing the risk of getting HIV before you get it.
What are the possible side effects of YEZTUGO?
- The most common side effects of YEZTUGO are injection site reactions, headache, and nausea. These are not the only possible side effects.
- Reactions at the injection site may include a lump or bump, pain, skin hardening, swelling, itching, redness, bruising, or warmth.
- Rarely, if YEZTUGO is injected incorrectly, serious injection site reactions, like severe damage of the skin or open sores, can occur.
- Tell your healthcare provider if you have any injection site reactions or other side effects that bother you or don’t go away.
What should I tell my healthcare provider before receiving YEZTUGO?
- All your medical conditions.
- If you are pregnant or plan to become pregnant. Tell your healthcare provider if you become pregnant while or after receiving YEZTUGO.
- If you are breastfeeding or plan to breastfeed. Talk to your healthcare provider about the best way to feed your baby while you are receiving YEZTUGO.
- All the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. YEZTUGO can remain in your body for up to 9 months after your last injection and can affect other medicines. Keep a list of all your medicines and show it to your healthcare provider and pharmacist. Do not start a new medicine without telling your healthcare provider.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.